Gut microbiota, epithelial function and derangements in obesity

Gut microbiota and obesity (microbiota, obesity, prebiotics)

Obesity, Diabetes, and Gut Microbiota

The connection between gut microbiota and energy homeostasis and inflammation and its role in the pathogenesis of obesity-related disorders are increasingly recognized. Animals models of obesity connect an altered microbiota composition to the development of obesity, insulin resistance, and diabetes in the host through several mechanisms: increased energy harvest from the diet, altered fatty ac...

Diet, Gut Microbiota and Obesity

Hongjie Li1,4* and Chuanxian Wei2,3* 1Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945-1400, USA 2State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, the Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China 3University of Chinese Academy of Sciences, Beijing, 100080, China 4Department of Biology, University of Rochester, River...

Changes in the composition and function of the gut microbiota in celiac disease

Evidence is supported the hypothesis that any changes in the composition and function of the gut microbiota play a fundamental role in a number of chronic inflammatory diseases including celiac disease (CD). In the last decade, several culture-independent methods have been developed to identify the components of the human microbiome. The study of microbiota based on nucleic acid analysis found ...

Gut microbiota in obesity and metabolic disorders.

Obesity is a major public health issue as it is causally related to several chronic disorders, including type-2 diabetes, CVD and cancer. Novel research shows that the gut microbiota is involved in obesity and metabolic disorders, revealing that obese animal and human subjects have alterations in the composition of the gut microbiota compared to their lean counterparts. Moreover, transplantatio...